research

Biobide takes part in a research about Malaria funded by Melinda and Bill Gates

Biobide (Bionaturis Group) has recently participated in a drug discovery research against malaria, a disease that causes about 440,000 deaths each year worldwide. The collaborative international project supported by Melinda and Bill Gates has the main goal of going from Hits to Leads among a selection of 400 compounds –included in the Malaria Box- to which researchers from 30 different countries have had access in the lastest two years. The final end is public institutions and the industry sharing more open knowledge in order to progress in new joint developments.

The promising results have just been published in a scientific paper and include the toxicity assays in zebrafish performed by Biobide to test the potential toxicity of the candidates to fight malaria. “Our presence in this study shows the versatility and usefulness of the zebrafish as animal model for drug discovery, as well as our expertise in this field. In addition to the obvious scientific value, this collaborative project has also a very relevant social value for Biobide, that is contributing in this way to find solutions for a disease that affected 95 countries worldwide in 2015”, the R&D Management Director at Biobide, Arantza Muriana, has stated.

In the 290 assays made by the different researchers for this study, 130 compounds have shown potential action against malaria which paves the way for a future election of the most suitable ones to develop new drugs. Additionally, some of these compounds have also shown outstanding activity against other disease agents, including bacteria, fungi, other parasites and even human cancer cells. In fact, these positive results have ignited over 30 drug development program devoted to fight different diseases. This initiative has been so satisfying that promoters are already repeating […]

August 2nd, 2016|Blog english|Comments Off|

The Journal of Biological Chemistry publishes the result of a research by BBD BioPhenix

Researchers of BBD BioPhenix-Biobide, company integrated in Bionaturis Group, has made an study for the pharmaceutical laboratory Sanofi in order to help them to confirm that some proteins present in hypoxic cells have an important function in the tumor growth. The result of the essay has recently been published in the well-regarded specialized magazine ‘The Journal of Biological Chemistry’.

The formation of new vessels in the tumor (angiogenesis) is essential for primary tumor growth and facilitates tumor invasion and metastasis. Hypoxia has been described as one trigger of angiogenesis. Indeed, hypoxia is a hallmark of solid tumors and has profound effects on the different components of the tumoral environment. For example, hypoxia is able to activate endothelial cells, leading to angiogenesis. In this study, they were identified some proteins involved in the hypoxia correlated with tumors, and the function of the identified sialoglycoproteins was assessed in a vasculogenesis assay in vivo in zebrafish by using morpholinos.

For further information, please click here

July 29th, 2015|Blog english|Comments Off|

2014, Year of Biotechnology in Spain

The biotech sector has one more reason to begin the new year with energy and eagerness, considering that 2014 has been quoted by the Spanish Government as the Year of Biotechnology. The Spanish Federation of Biotechnologists, along with the Spanish Society of Biotechnology (SEbiot), the Spanish Society of Microbiology (SEM), and the Spanish Association of Bio Enterprises (Asebio), have been the boosters of this initiative, which involves an important support for the industry and its professionals. In their words, the goal of this year is “not only continue encouraging the Spanish Biotech in all its sides, both research and industrial, but also improving its teaching and social concern. It’s about summing up, putting Biotech in the centre of society”.

Among the main goals of this commemoration, we have to highlight fostering Biotech research in Spain, the improvement of its teaching and dissemination, and the rise of the cooperation between the public and private sector in this field.

According to statistics from the Asebio annual report, the number of biotech companies grew more than 70% in 2011. Cataluña, Madrid and Adalucía –where Bionaturis is located- are the regions gathering more companies in this sector. The OECD ranked Spain in 2012 as the second country of the European Union with a bigger number of biotech companies.

Bionaturis congratulates the initiative and will support this commemoration, forecasting a great year for the global sector in which fostering R+D will have a key role.

Bionaturis will take part on a round table about Andalusian aquaculture R&D

Ana de las Heras, PhD in Veterinarian Sciences and scientist at Bionaturis, will take part on the conference called ‘R&D, an opportunity for the development of aquaculture in Andalusia’ on October 24th , organized by Ifapa (El Toruño Center) and the CAMPUS DE EXCELENCIA INTERNACIONAL DEL MAR” (CEIMAR) of Cadiz University (UCA).

Ana de las Heras will participate in the round table at 14.00 hours along with members of the companies Cupimar and Culmansur.

Check the full program and inscriptions here

October 18th, 2013|congress|0 Comments|

Spanish Pharmaceutical industry bets on research

The Spanish pharmaceutical industry keeps betting on research with an investment of 972 million Euros in 2012. Namely, the investment reached 200 million Euros at the biotechnology sector, 20% of the total budget.

The most important allocation -479 million- was dedicated to clinical trials, most of them in clinical phase III. It must be highlighted that the expense in clinical research has increased 86% in the last nine years. 45% of the budget was dedicated to research contracts with hospitals, universities and public institutions, an activity that increased nearly 5% in 2012.

According to the data of the survey made to members of Farmaindustria, the number of R&D hiring decreased 3,6% in relation to 2011. However, the qualification of the employees is getting higher and higher: four out of five are graduates and doctors. In general figures, Spain is the fourth country in Europe in pharmaceutical workforce with nearly 40,000 jobs.

These data show that, in spite of the present economic situation and the measures of control of expenses, the pharmaceutical industry is still one of the main driving forces of  Spanish R&D. 

Vaccines: the best mankind defense

A brief overview to the history of mankind shows the importance of vaccines and, therefore, of preventive medicine research. Although other threats exist nowadays, thanks to science and the development of new manufacturing platform of vaccines as FLYLIFE of Bionaturis, the world is better prepared than ever to halt the spread of either new or the resurgence of some of the most devastating pandemic episodes in history such as the Black Death, flu or smallpox. The invaluable effort of a lot of researchers and experts has it made possible along centuries that these huge pandemics have become history.

Click here to know how it has been achieved

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